Eliminate the uncertainty of your future
There is an increased likelihood of a BRCA1 or BRCA2 mutation in patients with certain personal and family history characteristics and various clinical criteria. BRCANOW® is a Next-Gen Sequencing (NGS)-based assay using a state-of-the-art platform to detect whether or not a mutation is present.
BRCANOW® is a next-generation sequencing panel for people with a personal or family history of breast or ovarian cancer.
For hereditary screening, we offer two versions of the BRCANOW® test, BRCANOW® Basic and BRCANOW® Extended, with reflex options available. In addition to BRCA1 & BRCA2, which account for the majority of hereditary breast and ovarian cancers, the BRCANOW® Extended panel includes additional genes that are less common but known to be associated with hereditary breast and ovarian cancers. Both versions of the assay utilize next-generation sequencing to detect single- and multi-nucleotide substitutions and small insertions and deletions in coding regions and exon-intron junctions, as well as large genomic rearrangements of the target genes, providing >1500X average coverage at the targeted genomic regions of the tested genes.
Risk of cancer in individuals with a BRCA1
or BRCA2 mutation
  • 80%
    Breast mutation BRCA1
  • 40%
    Ovarian mutation BRCA1
  • 30%
    Prostate mutation BRCA1
  • 3%
    Pancreatic mutation BRCA1
  • 70%
    Breast mutation BRCA2
  • 18%
    Ovarian mutation BRCA2
  • 39%
    Prostate mutation BRCA2
  • 7%
    Pancreatic mutation BRCA2
Most hereditary cancers
This COMPREHENSIVE GERMLINE PANEL analyzes 88 clinically-relevant genes that are associated with genetic disorders, including most hereditary cancers.
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Prostate cancer
PROSTATENOW™ is a germline test for people with prostate cancer. This test can be used to predict prognosis among men with localized prostate cancer, predict therapeutic responses for advanced patients, and predict cancer risk among unaffected men.
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Colorectal cancer
LYNCHNOW® is a cost-effective, screening tool that rapidly detects mutations that cause Lynch syndrome.
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We're here to guide you through the process.
BRCANOW® includes genetic counseling to walk you through our process and test results, along with any lifestyle or treatment alternatives depending on your results.